The efficacy of initial ventilation strategy for adult immunocompromised patients with severe acute hypoxemic respiratory failure: study protocol for a multicentre randomized controlled trial (VENIM)
作者: Tao WangGang LiuKun HeXin LuXianquan LiangMeng WangRong ZhuZongru LiFeng ChenJun KeQingming LinChuanyun QianBo LiJie WeiJingjun LvLi LiYanxia GaoGuofeng WuXiaohong YuWeiqin WeiYing DengFengping WangHong ZhangYun ZhengHong ZhanJinli LiaoYingping TianDongqi YaoJingsong ZhangXufeng ChenLishan YangJiali WuYanfen ChaiSongtao ShouMuming YuXudong XiangDongshan ZhangFengying ChenXiufeng XieYong LiBo WangWenzhong ZhangYongli MiaoMi
作者单位: 1Peking Union Medical College Hospital
2Guiyang Second People Hospital
3Beijing Tiantan Hospital, Capital Medical University
4Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University
5First Affiliated Hospital of Kunming Medical University
6Renmin Hospital of Wuhan University
7First Affiliated Hospital of Zhengzhou University
8Affiliated Hospital of Guizhou Medical University
9Affiliated Hospital of Guizhou
刊名: BMC Pulmonary Medicine, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12890-017-0467-6
关键词: Ventilation strategyNoninvasive mechanical ventilationInvasive mechanical ventilationAcute respiratory failureImmunocompromised patients
原始语种摘要: Acute respiratory failure (ARF) is still one of the most severe complications in immunocompromised patients. Our previous systematic review showed noninvasive mechanical ventilation (NIV) reduced mortality, length of hospitalization and ICU stay in AIDS/hematological malignancy patients with relatively less severe ARF, compared to invasive mechanical ventilation (IMV). However, this systematic review was based on 13 observational studies and the quality of evidence was low to moderate. The efficacy of NIV in more severe ARF and in patients with other causes of immunodeficiency is still unclear. We aim to determine the efficacy of the initial ventilation strategy in managing ARF in immunocompromised patients stratified by different disease severity and causes of immunodeficiency, and...
全文获取路径: Springer Nature  (合作)
影响因子:2.76 (2012)

  • ventilation 通风
  • hypoxemic 血氧不足的
  • respiratory 呼吸过程
  • controlled 受控
  • severe 严滥
  • efficacy 效验
  • failure 破坏
  • strategy 战略
  • noninvasive 非扩散的
  • trial 试验