Facile In Situ Preparation and In Vitro Antibacterial Activity of PDMAEMA-Based Silver-Bearing Copolymer Micelles
作者: Wenjing LinKaihang HuangYanzhe LiYanlin QinDi XiongJiabao LingGuobin YiZilun TangJinglian LinYunwei HuangChufen YangJufang Wang
作者单位: 1School of Chemical Engineering and Light Industry, Guangdong University of Technology
2School of Bioscience & Bioengineering, South China University of Technology
3School of Chemical Engineering, Xiangtan University
刊名: Nanoscale Research Letters, 2019, Vol.14 (1), pp.1-11
来源数据库: Springer Nature Journal
DOI: 10.1186/s11671-019-3074-z
关键词: AgNPsPolymer micellesStar polymerPDMAEMAAntimicrobials
英文摘要: Abstract(#br)Well-defined polymer micelles with core-shell structure are good delivery platform for stabilizing silver nanoparticles (AgNPs) in the field of antimicrobials targeting diseases. The rational construction of the polymer structure, an efficient, facile, and green preparation approach, and comprehensive exploration of the derived AgNPs are necessary, such as size, particle stability, antibacterial activity, and other properties. Herein, we designed and assessed the in vitro antimicrobial activity of AgNPs-decorated copolymer micelles with different copolymer topologies. First, linear or four-arm star triblock copolymers with the similar molecular weight and degree of polymerization were obtained, which consisted of DMAEMA for in situ reduction of silver ions to form AgNPs...
全文获取路径: Springer Nature  (合作)
影响因子:2.524 (2012)