Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis
作者: Qiang LiuHongfei ZhangXiaoli JiangCaiyun QianZhuoqi LiuDaya Luo
作者单位: 1Nanchang University
2Nanchang University, Nanchang
刊名: Molecular Cancer, 2017, Vol.16 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12943-017-0742-4
关键词: Cancer metastasisSeedSoilMetastasis research
英文摘要: Metastasis has intrigued researchers for more than 100 years. Despite the development of technologies and therapeutic strategies, metastasis is still the major cause of cancer-related death until today. The famous “seed and soil” hypothesis is widely cited and accepted, and it still provides significant instructions in cancer research until today. To our knowledge, there are few reviews that comprehensively and correlatively focus on both the seed and soil factors involved in cancer metastasis; moreover, despite the fact that increasingly underlying mechanisms and concepts have been defined recently, previous perspectives are appealing but may be limited. Hence, we reviewed factors involved in cancer metastasis, including both seed and soil factors. By integrating new concepts with the...
原始语种摘要: Metastasis has intrigued researchers for more than 100 years. Despite the development of technologies and therapeutic strategies, metastasis is still the major cause of cancer-related death until today. The famous “seed and soil” hypothesis is widely cited and accepted, and it still provides significant instructions in cancer research until today. To our knowledge, there are few reviews that comprehensively and correlatively focus on both the seed and soil factors involved in cancer metastasis; moreover, despite the fact that increasingly underlying mechanisms and concepts have been defined recently, previous perspectives are appealing but may be limited. Hence, we reviewed factors involved in cancer metastasis, including both seed and soil factors. By integrating new concepts with the...
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:5.134 (2012)

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关键词翻译
关键词翻译
  • hypothesis 假说
  • understanding 理解
  • metastasis 同质蜕变
  • involved 涉及
  • still 
  • more 更多
  • increasingly 愈加
  • development 开发
  • recently 近来
  • discuss 议论