Enhancement of thermoalkaliphilic xylanase production by Pichia pastoris through novel fed-batch strategy in high cell-density fermentation
作者: Tingting ShangDayong SiDongyan ZhangXuhui LiuLongmei ZhaoCong HuYu FuRijun Zhang
作者单位: 1China Agricultural University
2Henan University of Science and Technology
刊名: BMC Biotechnology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12896-017-0361-6
关键词: Thermoalkaliphilic xylanasePichia pastorisFermentation parameter optimizationBioprocessFed-batch strategyHigh cell-density fermentation
英文摘要: Xylanase degrades xylan into monomers of various sizes by catalyzing the endohydrolysis of the 1,4-β-D-xylosidic linkage randomly, possessing potential in wide industrial applications. Most of xylanases are susceptible to be inactive when suffering high temperature and high alkaline process. Therefore, it is necessary to develop a high amount of effective thermoalkaliphilic xylanases. This study aims to enhance thermoalkaliphilic xylanase production in Pichia pastoris through fermentation parameters optimization and novel efficient fed-batch strategy in high cell-density fermentation.
原始语种摘要: Xylanase degrades xylan into monomers of various sizes by catalyzing the endohydrolysis of the 1,4-β-D-xylosidic linkage randomly, possessing potential in wide industrial applications. Most of xylanases are susceptible to be inactive when suffering high temperature and high alkaline process. Therefore, it is necessary to develop a high amount of effective thermoalkaliphilic xylanases. This study aims to enhance thermoalkaliphilic xylanase production in Pichia pastoris through fermentation parameters optimization and novel efficient fed-batch strategy in high cell-density fermentation.
全文获取路径: Springer Nature  (合作)
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影响因子:2.165 (2012)

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关键词翻译
关键词翻译
  • strategy 战略
  • fermentation 发酵
  • through 经过
  • batch 一批
  • density 密度
  • xylanase 木聚糖酶
  • necessary 必要的
  • production 生产
  • Fermentation 发酵
  • effective 有效的