Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome
作者: Debora CompareAlba RoccoPietro CoccoliDebora AngrisaniCostantino SgamatoBarbara IovineUmberto SalvatoreGerardo Nardone
作者单位: 1University Federico II of Naples
刊名: BMC Gastroenterology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12876-017-0605-x
关键词: Post-infectious irritable bowel syndromeProbioticsPostbiotic
英文摘要: The evidence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convincing. Lactobacillus spp. positively affect IBS symptoms, although the mechanisms through which probiotics exert their beneficial effects are largely unknown. The aim of the study is to evaluate the role of Lactobacillus casei DG (LC-DG) and its postbiotic (PB) in modulating the inflammatory/immune-response in PI-IBS in an ex-vivo organ culture model.
原始语种摘要: The evidence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convincing. Lactobacillus spp. positively affect IBS symptoms, although the mechanisms through which probiotics exert their beneficial effects are largely unknown. The aim of the study is to evaluate the role of Lactobacillus casei DG (LC-DG) and its postbiotic (PB) in modulating the inflammatory/immune-response in PI-IBS in an ex-vivo organ culture model.
全文获取路径: Springer Nature  (合作)
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影响因子:2.11 (2012)

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关键词翻译
关键词翻译
  • irritable 易发怒的
  • bowel 
  • mucosal 粘膜的
  • microbiota 微生物区系
  • syndrome 症候群
  • infectious 传染性的
  • organ 
  • culture 
  • inflammatory 激怒的
  • modulating 调制的