MiRNAs regulate oxidative stress related genes via binding to the 3′ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis
作者: Changrui WuZhao LiuLe MaCheng PeiLi QinNing GaoJun LiYue Yin
作者单位: 1the First Affiliated Hospital of Medical School of Xi’an Jiaotong University
2Xi’an Jiaotong University Health Science Center
3Xi’an Jiaotong University
刊名: BMC Ophthalmology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12886-017-0537-9
关键词: CataractOxidative stressMiRNAs
英文摘要: Age-related cataracts are related to oxidative stress. However, the genome-wide screening of cataract related oxidative stress related genes are not thoroughly investigated. Our study aims to identify cataract regulated miRNA target genes that are related to oxidative stress and to propose a new possible mechanism for cataract formation.
原始语种摘要: Age-related cataracts are related to oxidative stress. However, the genome-wide screening of cataract related oxidative stress related genes are not thoroughly investigated. Our study aims to identify cataract regulated miRNA target genes that are related to oxidative stress and to propose a new possible mechanism for cataract formation.
全文获取路径: Springer Nature  (合作)
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影响因子:1.444 (2012)

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关键词翻译
关键词翻译
  • cataract 急流
  • stress 应力
  • oxidative 氧化的
  • related 有关的
  • pathogenesis 发病机理
  • binding 装订
  • hypothesis 假说
  • regulate 控制
  • possible 可能的
  • screening 筛分