Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella
作者: Yang LiuYanan GaoXiaohong LiuQin LiuYuanxing ZhangQiyao WangJingfan Xiao
作者单位: 1East China University of Science and Technology
2Shanghai Engineering Research Center of Maricultured Animal Vaccines
3Shanghai Collaborative Innovation Center for Biomanufacturing
刊名: BMC Microbiology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12866-017-1013-7
关键词: Plasmid conjugationEdwardsiella PiscicidaTisT4SSRNA-seqEsrB
原始语种摘要: Conjugation is a major type of horizontal transmission of genes that involves transfer of a plasmid into a recipient using specific conjugation machinery, which results in an extended spectrum of bacterial antibiotics resistance. However, there is inadequate knowledge about the regulator and mechanisms that control the conjugation processes, especially in an aquaculture environment where a cocktail of antibiotics may be present. Here, we investigated these with pEIB202, a typical multi-drug resistant IncP plasmid encoding tetracycline, streptomycin, sulfonamide and chloramphenicol resistance in fish pathogen Edwardsiella piscicida strain EIB202.
全文获取路径: Springer Nature  (合作)
影响因子:3.104 (2012)

  • conjugation 共轭
  • sequencing 排序
  • genetic 遗传的
  • major 知的
  • plasmid 质粒
  • trait 性状
  • aquaculture 水培
  • bacterial 细菌的
  • cocktail 鸡尾酒