Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Pulmonary Thromboembolism
作者: YesilkayaKarkucakCobanUrsavasTureYakut
作者单位: 1Department of Pulmonary Medicine , Samsun Hospital for Pulmonary Diseases , Samsun , Turkey
2Department of Medical Genetics , Sakarya University Training and Research Hospital , Sakarya , Turkey
3Department of Pulmonary Medicine , Sakarya University Training and Research Hospital , Sakarya , Turkey
4Department of Pulmonary Medicine , Uludag University, Medical Faculty , Bursa , Turkey
5Department of Medical Genetics , Uludag University, Medical Faculty , Bursa , Turkey
刊名: International Journal of Human Genetics, 2015, Vol.15 (4), pp.183-189
来源数据库: Taylor & Francis Journal
DOI: 10.1080/09723757.2015.11886266
原始语种摘要: Abstract(#br)The aim of the present study is to investigate the relationship between angiotensin-converting enzyme (ACE) gene polymorphism and pulmonary embolism by comparing the frequency of ACE gene polymorphism between cases diagnosed with pulmonary embolism with that of the control group. The study included 73 patients and 73 healthy subjects as the control group. Isolated DNAs were genotyped using the polymerase chain reaction (PCR) method for the identification of the ACE insertion/deletion (I/D) polymorphism. The genotypes were determined according to the bands observed in the agarose gel electrophoresis. The frequency of ID genotype was 39.7 percent, the frequency of insertion/insertion (II) genotype was 17.8 percent, and the frequency of the deletion/deletion (DD) genotype was...
全文获取路径: Taylor & Francis  (合作)
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关键词翻译
关键词翻译
  • polymorphism 多晶形
  • genotype 属型
  • investigate 
  • embolism 栓塞
  • percent 百分率
  • insertion 插入
  • deletion 缺失
  • included 内藏的
  • bands 同心带
  • control 控制