| 作者： | Yesilkaya, Karkucak, Coban, Ursavas, Ture, Yakut |
| 作者单位： |
1Department of Pulmonary Medicine , Samsun Hospital for Pulmonary Diseases , Samsun , Turkey 2Department of Medical Genetics , Sakarya University Training and Research Hospital , Sakarya , Turkey 3Department of Pulmonary Medicine , Sakarya University Training and Research Hospital , Sakarya , Turkey 4Department of Pulmonary Medicine , Uludag University, Medical Faculty , Bursa , Turkey 5Department of Medical Genetics , Uludag University, Medical Faculty , Bursa , Turkey |
| 刊名： | International Journal of Human Genetics, 2015, Vol.15 (4), pp.183-189 |
| 来源数据库： | Taylor & Francis Journal |
| DOI： | 10.1080/09723757.2015.11886266 |
| 原始语种摘要： | Abstract(#br)The aim of the present study is to investigate the relationship between angiotensin-converting enzyme (ACE) gene polymorphism and pulmonary embolism by comparing the frequency of ACE gene polymorphism between cases diagnosed with pulmonary embolism with that of the control group. The study included 73 patients and 73 healthy subjects as the control group. Isolated DNAs were genotyped using the polymerase chain reaction (PCR) method for the identification of the ACE insertion/deletion (I/D) polymorphism. The genotypes were determined according to the bands observed in the agarose gel electrophoresis. The frequency of ID genotype was 39.7 percent, the frequency of insertion/insertion (II) genotype was 17.8 percent, and the frequency of the deletion/deletion (DD) genotype was... |