Angiogenesis in salivary gland tumors: from clinical significance to treatment
作者: Stamatios TheocharisGeorge GribilasConstantinos GiaginisEfstratios PatsourisJerzy Klijanienko
作者单位: 1University of Athens, Medical School, First Department of Pathology , 11527 Athens, Greece
2Curie Institut, Department of Pathology , 75248 Paris, France
3University of the Aegean, School of Environment, Department of Food Science and Nutrition , Mitropoliti Ioakeim Street, Myrina, Lemnos 81400, Greece +30 22540 83117 ; +30 22540 83109 ;
刊名: Expert Opinion on Therapeutic Targets, 2015, Vol.19 (6), pp.807-819
来源数据库: Taylor & Francis Journal
DOI: 10.1517/14728222.2015.1016424
关键词: AngiogenesisBiomarkersDiagnosisMicrovessel densityPrognosisSalivary glands tumorsTreatmentVEGF
原始语种摘要: Introduction: (#br) Salivary gland tumors (SGTs) represent a rare cancer entity, consisting of various morphological features that complicate diagnosis. Their diversity in terms of morphology and clinical course makes defining risk factors difficult, while the molecular steps responsible for SGT development remain unclear. Angiogenesis, a hallmark of cancer development, is considered as an attractive target.(#br) Areas covered: (#br) This review aims to summarize the available research regarding angiogenesis in SGTs from clinical significance to treatment options.(#br) Expert opinion: (#br) The available data suggest that microvessel density (MVD) evaluation may be capable of discriminating between benign and malignant SGTs, while the use of CD105 antibody seems to be the most suitable....
全文获取路径: Taylor & Francis  (合作)
影响因子:4.13 (2012)

  • salivary 唾液的
  • gland 
  • significance 显著性
  • adenoid 腺样的
  • density 密度
  • discriminating 区分
  • treatment 处理
  • opinion 意见
  • prognostic 预测的
  • predictive 预言