Efficient atom-economic one-pot multicomponent synthesis of benzylpyrazolyl coumarins and novel pyrano[2,3-c]pyrazoles catalysed by 2-aminoethanesulfonic acid (taurine) as a bio-organic catalyst
作者: Asha V. ChateBadrodin Ayyub ShaikhGiribala M. BondleSunil M. Sangle
作者单位: 1Department of Chemistry , Dr. Babasaheb Ambedkar Marathwada University , Aurangabad , India
2;Rajaram College , Kolhapur , India
刊名: Synthetic Communications, 2019, Vol.49 (17), pp.2244-2257
来源数据库: Taylor & Francis Journal
DOI: 10.1080/00397911.2019.1619772
关键词: 2-Aminoethanesulfonic acidBenzylpyrazolyl coumarinGreen reactionMulticomponent reactionPyrano[23-c]pyrazoles
原始语种摘要: Abstract(#br)The present work describes eco-friendly multicomponent protocol for the synthesis in excellent yields of structurally diverse benzylpyrazolyl coumarin 5 (a–s)(#br) involving the reaction of 4-hydroxycoumarin, ethyl acetoacetate, hydrazine hydrate/phenyl hydrazine hydrate and aldehydes, also novel pyrano[2,3-c]pyrazole derivatives 8 (a–k)(#br) integrated by isonicotinic acid hydrazide from reaction of aldehyde, ethyl acetoacetate, malononitrile with isoniazid, employing water as a reaction medium and 2-aminoethanesulfonic acid (taurine) as the catalyst. This new methodology endowed the advantages such as short reaction time, recovery of catalysts after catalytic reaction and reusing them without losing their activity and alleviate of operation.
全文获取路径: Taylor & Francis  (合作)
分享到:
来源刊物:
影响因子:1.06 (2012)

×
关键词翻译
关键词翻译
  • taurine 牛磺酸
  • aldehyde 
  • reaction 反酌
  • multicomponent 多部件
  • catalyst 催化剂
  • novel 长篇小说
  • synthesis 合成
  • acetoacetate 乙酰醋酸盐
  • hydrazine 联氨
  • pyrazole 吡唑