Separation and Identification of Oligomeric-Hindered Amine Light Stabilizer Uvasorb HA 88 by High-performance Liquid Chromatography (HPLC) Coupled With Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALSI-TOF-MS)
作者: Yan LiLei Chen
作者单位: 1School of Pharmaceutical Science and Technology , Tianjin University , Tianjin , China
刊名: Analytical Letters, 2019, Vol.52 (16), pp.2546-2561
来源数据库: Taylor & Francis Journal
DOI: 10.1080/00032719.2019.1617731
关键词: High-performance liquid chromatography (HPLC)Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS)Uvasorb HA 88
原始语种摘要: Abstract(#br)Uvasorb HA 88 is widely used as a light stabilizer to prevent plastic polymer degradation. Its high molecular weight and oligomeric characters provide challenge for quality control. In this study, high-performance liquid chromatography (HPLC) coupled with electrospray ionization time of flight mass spectrometry (ESI-TOF MS) was applied for separation and detection of Uvasorb HA 88. The synthesis scheme was deduced and confirmed by the characterization of Uvasorb HA 88 products from different batches. Direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) was employed for the detailed characterization of chemical composition of Uvasorb HA 88. Furthermore, a reliable reversed-phase high-performance liquid chromatography (RP-HPLC)...
全文获取路径: Taylor & Francis  (合作)
影响因子:0.965 (2012)

  • performance 性能
  • HPLC 高效液相色谱法
  • liquid 液体
  • chromatography 色层分离法
  • ionization 电离化
  • flight 飞行
  • reversed 倒转的
  • spectrometry 光谱测定
  • coupled 耦合
  • scheme 略图