Optimization of the sublethal dose of silver nanoparticle through evaluating its effect on intestinal physiology of Nile tilapia ( Oreochromis niloticus L.)
作者: Biplab SarkarMayuree JaisaiArabinda MahantyPragnya PandaMohammad SadiqueB. B. NayakG. GallardoD. ThakurSurajit BhattacharjeeJoydeep Dutta
作者单位: 1National Institute Abiotic Stress Management , Baramati, Pune , Maharashtra , India
2School of Biotechnology , KIIT University , Patia, Bhubaneswar , India
3Centre of Excellence in Nanotechnology , Asian Institute of Technology , Pathum Thani , Thailand
4Imgenex India Limited, Patia , Bhubaneswar , Odisha , India
5Central Characterization Cell , Institute of Mineral and Materials Technology , Bhubaneswar , Odisha , India
6Chair in Nanotechnology , Water Research Center , Sultan Qaboos University , Al Khodh , Oman
7Department of Molecular Biology & Bioinformatics , Central University , Tripura , India
刊名: Journal of Environmental Science and Health, Part A, 2015, Vol.50 (8), pp.814-823
来源数据库: Taylor & Francis Journal
DOI: 10.1080/10934529.2015.1019800
关键词: Silver nanoparticleintestinesublethal toxicityNile tilapiagut microfloraimmunohistochemistry
原始语种摘要: Silver nanoparticles (SNPs) are widely used in a variety of biomedical and consumer products as an antimicrobial additive. The present study was conducted to evaluate the impacts of low-dose SNPs on intestinal physiology of tilapia ( Oreochromis niloticus L.) for assessing its apparent environmental risk due to extensive commercial use. SNPs were synthesized by a chemical reduction method yielding 1–27 nm oval shaped particles. Early fingerlings of tilapia were exposed with two sublethal concentrations (0.8 and 0.4 mg L−1) of SNPs for twenty one days period and its impact on the intestinal physiology was evaluated by histochemistry, catalase expression, glutamate dehydrogenase activity, SDS-PAGE and gut micro flora count. Histological analysis showed thinning of intestinal...
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