Depletion of penicillin G residues in tissues, plasma and injection sites of market pigs injected intramuscularly with procaine penicillin G
作者: G. O. KorsrudC. D. C. SalisburyC. S. RhodesM. G. PapichW. D. G. YatesW. S. BulmerJ. D. MacNeilD. A. LandryG. LambertM. S. YongL. Ritters
作者单位: 1Canadian Food Inspection Agency, Health of Animals Laboratory, Centre for Veterinary Drug Residues, Saskatoon, Saskatchewan, Canada
2Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
3Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada,College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA
4Canadian Food Inspection Agency, Health of Animals Laboratory, Centre for Veterinary Drug Residues, Saskatoon, Saskatchewan, Canada,Animal Diseases Research Institute, Lethbridge, Alberta, Canada
5Canadian Food Inspection Agency, Health of Animals Laboratory, Centre for Veterinary Drug Residues, Saskatoon, Saskatchewan, Canada;
刊名: Food Additives & Contaminants: Part A, 1998, Vol.15 (4), pp.421-426
来源数据库: Taylor & Francis Journal
DOI: 10.1080/02652039809374662
关键词: procaine penicillin Gdepletionmarket pigstissuesplasmainjection sites
原始语种摘要: Procaine penicillin G was administered by intramuscular (IM) injection to groups of healthy 100 kg market pigs at the approved label dose (15000 IU/kg body weight), once daily for three consecutive days; or an extra-label dose (66000 IU/kg body weight), once daily for five consecutive days. Penicillin G residue depletion was followed in plasma, tissue and injection sites using a liquid chromatographic method. Groups of pigs were killed 1, 2, 3, 4, 5 and 8 days after the last injection with the label dose. Penicillin G was not detected in liver after 1 day of withdrawal, in muscle and fat after 2 days of withdrawal, in plasma after 4 days of withdrawal, in skin after 5 days of withdrawal, or in kidney and the injection sites after 8 days of withdrawal. Other groups of pigs were killed...
全文获取路径: Taylor & Francis  (合作)
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影响因子:2.22 (2012)

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