Review of Antibiotic Dosing with Peritonitis in APD
作者: Ann ManciniBeth Piraino
刊名: Peritoneal Dialysis International, 2019, Vol.39 (4), pp.299-305
来源数据库: Multimed
关键词: Automated peritoneal dialysisPharmacokinetics
原始语种摘要: Peritonitis is the leading cause of transfer from peritoneal dialysis (PD) to hemodialysis (HD). It is also the leading causeof hospitalization of PD patients. The usual treatment of peritonitis for automated PD (APD) patients consists of antibioticsgiven once daily in the long dwell. However, the once-daily antibiotic dosing recommendations are based primarily on studieswith continuous ambulatory PD (CAPD) regimens. Published studies on antibiotic dosing in APD are very limited. We will reviewthe scant literature on this topic. It is possible that extrapolating once-daily dosing from CAPD to APD may lead to underdosing.There is a need for further pharmacokinetic studies of antibiotic dosing in APD.
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  • dosing 配量
  • antibiotic 抗生素
  • APD Application Program Division
  • dialysis 透析
  • peritoneal 腹膜的
  • peritonitis 腹膜炎
  • ambulatory 步行的
  • daily 每天的
  • dwell 居住
  • scant 不足的