Bone infections and bone graft substitutes for local antibiotic therapy.
作者: Fani LalidouGeorge KoliosGeorgios I Drosos
作者单位: 1Medical School, Democritus University of Thrace Alexandroupolis, Greece.
2Laboratory of Pharmacology Medical School Democritus University of Thrace Alexandroupolis, Greece.
3Department of Orthopaedic Surgery Medical School, Democritus University of Thrace University General Hospital of Alexandroupolis Alexandroupolis, Greece.
刊名: Surgical technology international, 2014, Vol.24
来源数据库: Surgical Technology Online
原始语种摘要: Osteomyelitis is a bone infection by micro-organisms. Despite advances in antibiotics and operative techniques, osteomyelitis remains an orthopaedic challenge and expensive to treat. Antimicrobial therapy is adequate for the treatment of most cases of acute osteomyelitis of any type, provided that diagnosis is made early. The treatment of chronic osteomyelitis is operative followed by adjunctive antibiotic therapy. Apart from surgical debridement and systemic antibiotic treatment, local antibiotic treatment by using various antibiotic delivery vehicles is a preferred method by most surgeons. Antibiotic-loaded bone cement (polymethylmethacrylate, PMMA) is the most widely used material and represents the current standard as an antibiotic delivery vehicle in orthopaedic surgery. Despite...
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  • antibiotic 抗生素
  • osteomyelitis 骨髓炎
  • graft 嫁接
  • orthopaedic 矫形术的
  • operative 有法律效力
  • debridement 清创术
  • local 局部的
  • loaded 加负荷的
  • treatment 处理
  • biodegradable 生物降解的