WHAT’S YOUR POISON? IMPACT OF INDIVIDUAL REPAIR CAPACITY ON THE OUTCOMES OF GENOTOXIC THERAPIES IN CANCER. PART I – ROLE OF INDIVIDUAL REPAIR CAPACITY IN THE CONSTITUTION OF RISK FOR LATE-ONSET MULTIFACTORIAL DISEASE
作者: Rumena PetkovaPavlina ChelenkovaElena GeorgievaStoian Chakarov
作者单位: 1Scientific Technological Service (STS), Sofia, Bulgaria
2Sofia University “St. Kliment Ohridsky, Faculty of Biology, Sofia, Bulgaria
刊名: Biotechnology & Biotechnological Equipment, 2013, Vol.27 (6), pp.4208-4216
来源数据库: Diagnosis Press Journal
DOI: 10.5504/BBEQ.2013.0097
关键词: DNA repairindividual repair capacityriskbiomarkerstoxicity
原始语种摘要: The capacity for repair of damage in DNA may vary between clinically healthy people and in patients with different diseases and conditions, contributing to the risk for development of late-onset multifactorial disease, eligibility for different therapies and various therapy-related complications. At present, the effects of individual variance in DNA repair capacity in human disease are best studied in cancer. The first part of this paper briefly reviews the history of the field and the currently available biomarkers of individual repair capacity associated with the risk for development of cancer and other late-onset multifactorial diseases and conditions.
全文获取路径: Diagnosis Press 
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关键词翻译
关键词翻译
  • conditions 条件式
  • studied 学习
  • multifactorial 多因子的
  • various 千变万化的
  • capacity 电容量
  • effects 海员自身物品
  • present 出席的
  • repair 修理
  • first 第一
  • related 有关的