HEMOPHAGOCYTIC SYNDROME: A Rare Life-Threatening Complication of Visceral Leishmaniasis in a Young Boy
作者: Bahattin Tun&ccedilAli Ayata
刊名: Pediatric Hematology-Oncology, 2001, Vol.18 (8), pp.531-536
来源数据库: Informa Journal
DOI: 10.1080/088800101753328501
原始语种摘要: The authors report a case of hemophagocytic syndrome (HPS) associated with acute visceral leishmaniasis (VL). A 4-year-old boy was admitted with high fever, hepatosplenomegaly, and pancytopenia. Elevated serum ferritin and triglyceride, low fibrinogen levels, and bone-marrow (BM) histiocytic hyperplasia with prominent hemophagocytosis were consistent with a HPS. An initial diagnosis of kala-azar was refuted because of negativity of BM aspiration and serology for this parasite, and the diagnosis of HPS was made. Three months after first admission, reevaluation of the BM aspiration revealed many amastigotes of Leishmania parasites. The serology of VL became positive, finally establishing the diagnosis of VL. Although specific therapy for VL was instituted, the patient died 4 weeks after the...
全文获取路径: Informa Healthcare 
影响因子:0.895 (2012)

  • parasite 寄生物
  • Leishmania 利什曼虫
  • leishmaniasis 利什曼病
  • reevaluation 重估计
  • diagnosis 特镇述
  • serology 血清学
  • aspiration 愿望
  • fibrinogen 纤朊原
  • pancytopenia 膏血细胞减少
  • ferritin 铁蛋白