Isolation of Natural Derivated Steroidal from Bark Stem of Melochia umbellata (Houtt) Stapf var. degrabrata K.
作者: Usman Usman Nunuk Hariani Soekamto Muhammad NatsirMaulidiyah Maulidiyah
刊名: Asian Journal of Chemistry, 2020, Vol.32 (4)
来源数据库: Asian Journal of Chemistry
DOI: 10.14233/ajchem.2020.22414
关键词: M. umbellataStem barkSteroid compoundsToxicityArtemia salina.
原始语种摘要: Exploration of the natural product as pharmaceutical drug widely discover continuously for human life. The unique chemical compounds have been explored from bark stem of Melochia Umbellata (Houtt) Stapf var. degrabrata K. (M. umbellata) which is obtained from South Sulawesi, Indonesia. We discovered two group compounds isolated namely stigmasta-5,22-dien-3-β-ol (1) and stigmasta-5,22-dien-on (2), from n-hexane and chloroform extracts. The chemical structure of compounds 1 and 2 were identified based on IR spectroscopic, 1H NMR and 13C NMR and compared spectra data with data of compounds by other researchers. Compounds 1 and 2 are evaluated of their toxicity activity against shrimp larvae (Artemia salina) shows that the compound 1 shows weak toxicity activities against Artemia salina with...
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  • Artemia 天南属
  • compounds 化合物
  • salina 盐碱滩
  • larvae 幼虫
  • shrimp 小虾
  • chemical 化学的
  • bioactivity 生物活性
  • hexane 己烷
  • toxicity 毒性
  • chloroform 氯仿