Curcumin Prevents Renal Dysfunction, Proteinaceous and Granular Cast Formation in Tubular Lumen in Kidney of Mice Exposed to Formaldehyde Inhalation
作者: Joyce Trujillo
刊名: Current Topics in Nutraceutical Research, 2019, Vol.17 (3)
来源数据库: New Century Health Publishers, LLC
关键词: C57BL/6 miceCurcuminFormaldehyde inhalationKidney dysfunctionOxidative stressRenal damage
原始语种摘要: Formaldehyde is a volatile chemical compound that is commonly used in the chemical industry. Formaldehyde inhalation exposure has been associated with cancer, respiratory diseases, digestive and neurological disorders. Oxidative stress is one of the potential mechanisms by which formaldehyde inhalation induces toxicity. Curcumin is a natural compound endowed with antioxidant properties and my thus prevent formaldehyde-induced toxicity. This study aimed to examine the effects of formaldehyde inhalation on renal function and kidney structure of mice; the potential protective effects of curcumin administration against kidney dysfunction, renal damage and oxidative stress were also investigated. Formaldehyde inhalation induced renal dysfunction and damage, as shown by the increase of serum...
全文获取路径: NCHP, LLC 

  • inhalation 吸入
  • formaldehyde 甲醛
  • induced 感应的
  • potential 
  • renal 肾的
  • curcumin 姜黄色素
  • against 反对
  • dysfunction 功能障碍
  • toxicity 毒性
  • antioxidant 抗氧化剂