α-Glucosidase Inhibitory Compounds in Malus Halliana Koehne Tea
作者: Fajin Feng
刊名: Current Topics in Nutraceutical Research, 2019, Vol.17 (3)
来源数据库: New Century Health Publishers, LLC
关键词: Α-GlucosidaseChemical compositionInhibitory activityMalus halliana Koehne tea
原始语种摘要: The aim of this study was to isolate a-glucosidase inhibitory constituents from Malus halliana Koehne tea. The ethyl acetate and n-butanol extract of M. halliana tea showed α-glycosidase inhibitory activity (IC50 332.24 and 168.92 μg/mL, respectively) and eleven compounds (1–11) were isolated and identified by extensive NMR data (1H and 13C NMR) and mass spectrum. Eleven compounds were isolated from this plant for the first time, and compounds 2, 4, 5, 7 and 8 were isolated from the genus for the first time. The α-glucosidase inhibitory activity of compounds 6, 8, 9 and 10 (IC50 6.32, 15.53, 37.68 and 7.87 μM) were better than that of other compounds (IC50 > 200 μM). Compounds 1~5 and 11 displayed moderate inhibitory effects on α-glucosidase, with IC50 values of 226.76~435.56 μM, whereas...
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关键词翻译
关键词翻译
  • Malus 马吕斯座
  • isolated 隔离
  • inactive 不活泼的
  • glucosidase 葡萄糖苷酶
  • extensive 广泛的
  • inhibitory 禁止的
  • whereas 鉴于
  • activity 活度
  • acarbose 阿卡波糖
  • lower 降下