Evaluation of Serum Lipids and C-peptide among Breast Cancer Patients with Chemotherapy
作者: Anil Singh BasnyatPrabin Prabin GyawaliAbimanyu JhaPrabodh RisalBhupal Govinda Shrestha
作者单位: 1Department of Biotechnology, Kathmandu University
2Kathmandu University, School of Medical Sciences
3Institute of Medicine, Maharajgunj Medical Campus, Tribhuwan Univeristy Teaching Hospital
4School of ScienceKathmandu University
刊名: Annals of Clinical Chemistry and Laboratory Medicine, 2017, Vol.2 (2), pp.8-14
来源数据库: Annals of Clinical Chemistry and Laboratory Medicine
DOI: 10.3126/acclm.v2i2.15589
关键词: Breast cancerchemotherapyC-peptidelipid profile.
原始语种摘要: Background: Chemotherapy agents alter serum lipids and C-peptide in cancer patients increased incidence of cardiovascular disorders and diabetes, although mechanisms for these are not known. Diabetes and cardiovascular riskis the highly concerned chemotherapy induced complications among cancer patients. This study is aimed to evaluate the serum lipids and C-peptide in breast cancer patients receiving chemotherapy. Methods: This cross-sectional study includes160 individuals comprising 80 breast cancer patients and 80 controls with age ranges from 24 to 76 years. Patients received at least 3 cycles of chemotherapy. Serum Total cholesterol (TC), high density lipoprotein cholesterol (HDL) andC-peptide level was measuredin random blood sampleswhereas,other lipid parameters like Non HDL...
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  • cholesterol 胆甾醇
  • chemotherapy 化学疗法
  • lipids 类脂
  • breast 胸部
  • lipoprotein 脂蛋白
  • peptide 
  • diabetes 糖尿病
  • density 密度
  • statistically 统计地
  • controls 控制机构