TRANSFERSOMAL GEL CONTAINING GREEN TEA (CAMELLIA SINENSIS L. KUNTZE) LEAVES EXTRACT: INCREASING IN VITRO PENETRATION
作者: Effionora AnwarTahmida Diazputri UtamiDelly Ramadon
作者单位: 1Faculty of Pharmacy, Laboratory of Pharmaceutics and Pharmaceutical Technology, Universitas Indonesia, Depok, West Java, Indonesia.. effi.nora@gmail.com
刊名: Asian Journal of Pharmaceutical and Clinical Research, 2017, Vol.10 (8), pp.294-298
来源数据库: Innovare Academics Sciences PVT.Ltd.
DOI: 10.22159/ajpcr.2017.v10i8.19124
原始语种摘要: Objective: The aim of this study was to increase penetration of EGCG from green tea leaves extract (Camellia sinensis L. Kuntz) through the skin by formulating them into a transfersomal gel.Methods: Transfersomes were prepared by thin-layer hydration method, with different concentration of the extract that equivalent to 1% (F1), 1.5% (F2), and 2% (F3) EGCG. Transfersomes formula with good characteristics would be incorporated into a gel formulation. A gel without transfersomes prepared as a control of comparison. Both of gels were evaluated their physicochemical properties. In vitro penetration test using Franz diffusion cell with the skin of female Sprague-Dawley rats was also performed.Results: The results showed that F1 had the best physicochemical properties. F1 had a spherical shape,...
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关键词翻译
关键词翻译
  • penetration 穿透
  • increase 增加
  • efficiency 效率
  • properties 道具
  • formulating 公式制定
  • formulation 配方
  • respectively 分别
  • through 经过
  • entrapment 诱陷
  • their 他们的