Surgical treatment for heart failure: cell-based therapy with engineered tissue
作者: Jordan J. Lancaster Jen Watson Koevary Ikeotunye Royal Chinyere Sherry L. Daugherty Kenneth A. Fox Steven Goldman
刊名: Vessel Plus, 2019, Vol.3 (9)
来源数据库: OAE Publishing Inc.
DOI: 10.20517/2574-1209.2019.16
关键词: Heart failureInduced pluripotent stem cellsTissue engineering
原始语种摘要: This review will outline cell-based therapy for heart failure focusing on tissue engineering to deliver cells to the damaged heart. We will present an overview of the central approaches focusing on pluripotent stem cell-derived cells, mechanisms of action, autologous vs. allogeneic cell approaches, immunologic modulation, and safety considerations. We will outline the progress that has been made to-date and define the areas that still need to be investigated in order to advance the field.
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  • pluripotent 多能的
  • failure 破坏
  • heart 心脏
  • tissue 组织
  • immunologic 免疫的
  • damaged 残损
  • engineering 工程
  • cells 麻风细胞
  • deliver 输送
  • outline 轮廓