Article: Does IL-17F Play a Role inEtiology of TS? A Family Based Study
作者: Zuzhou Huang Ru Zhang Jiang Li Zhongcui Jing Xuewen Jia Chang Liu Chunmei Wu Shiguo Liu
刊名: Chronic Diseases Prevention Review, 2017, Vol.1 (1), pp.10-15
来源数据库: Guoyu exquisite culture Co., Ltd
原始语种摘要: Previous studies have suggested a critical role forinterleukin IL-17F in innate and adaptive immunity in vivoand its abnormal expression was found to play a bridgingrole in several neurological disorders. In this study, weinvestigated the association between functionalpolymorphisms in IL-17F and Tourette’s syndrome (TS) in aChinese Han population. We recruited 407 TS nuclear familytrios (325 male cases and 82 female cases each with theirparents) and 417 controls (321 male and 96 female), andperformed TaqMan allelic discrimination real-time PCR togenotype two polymorphisms in IL-17F, rs1889570 andrs763780. The transmission disequilibrium test (TDT) andhaplotype relative risk (HRR) were used to estimate geneticsusceptibility. In addition, we designed a classiccase–control study to identify...
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  • several 各自
  • female 女性的
  • relative 相对的
  • expression 表示
  • estimate 估计
  • addition 添加
  • Article 物品
  • found 创立
  • designed 设计了的计划了的
  • nuclear 原子核的