Lymph node isolated tumor cells and micrometastases in pathological stage I non-small cell lung cancer: prognostic significance
作者: Ottavio RenaLuca CarsanaSilvia CristinaEsther PapaliaFabio MasseraLuca ErricoCristina BozzolaCaterina Casadio
作者单位: 1a Department of Thoracic Surgery, University of Eastern Piedmont, Novara, Italy
2 b Department of Pathology, University of Eastern Piedmont, Novara, Italy
刊名: European Journal of Cardio-Thoracic Surgery, 2007, Vol.32 (6), pp.863-867
来源数据库: Oxford University Press
DOI: 10.1016/j.ejcts.2007.09.014
原始语种摘要: Objective: To determine the prevalence and prognostic significance of lymph node micrometastases and isolated tumor cells (ITC) in patients submitted for radical resection for pathological stage I non-small cell lung cancer (NSCLC). Methods: From January 1998 through December 2005, 87 consecutive pT1-2, pN0 NSCLC patients were enrolled. Surgical specimens were submitted to pathological routine examinations to define histotype, grade, stage, vascular invasion, necrosis and tumor proliferative index. A total of 694 regional lymph nodes were examined by means of serial sections stained with hematoxylin and eosin and labelled by immunohistochemistry (antibody AE1/AE3, DAKO). Relationships between these parameters and patients’ prognosis were investigated. Results: By histological examination,...
全文获取路径: Oxford U Press 
影响因子:2.674 (2012)

  • pathological 病理学的
  • prognostic 预测的
  • adenocarcinoma 腺癌
  • stage 
  • significance 显著性
  • lymph 淋巴
  • cancer 癌症
  • survival 生存
  • tumor 肿胀
  • prognosis 预报