Synthesis, Characterization, in vitro Antimicrobial, and Anthelmintic Evaluations of N-(4, 6-dimethylpyrimidin-2-yl)-4-((2-hydroxynaphthalen-1-yl) diazenyl) Benzene Sulfonamide and Its Metal (II) Complexes
作者: Jagdish Badgujar Dhananjay More Jyotsna Meshram
刊名: Modern Organic Chemistry Research, 2017, Vol.2 (2)
来源数据库: Isaac Scientific Publishing
关键词: Azo dyesulfonamidemetal complexesantimicrobial activityanthelmentic activity.
原始语种摘要: As a part of systematic investigation of biologically active compound, new azo dye ligand N-(4, 6-dimethylpyrimidin-2-yl)-4-((2-hydroxynaphthalen-1-yl) diazenyl) benzene sulfonamide has been synthesized by diazotization of 4-amino-N-(4, 6-dimethylpyrimidin-2-yl) benzenesulfonamide and coupled with coupling compound, naphthalen-2-ol. A new series of Ni (II), Cu (II), and Zn (II) complexes derived from this azo dye ligand (L) were synthesized. The structures of the ligand and metal complexes were confirmed by spectroscopic studies (elemental analysis, IR, 1H NMR and mass spectra). The azo dye and its complexes have been screened for their in vitro antimicrobial activities against some bacterial stains and fungal strains by disc diffusion method. The results showed that, the presence of...
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  • 二氮烯基 Interactive Interface
  • II Interactive Interface
  • diazenyl Interactive Interface
  • elemental 元素的
  • coupling 连接
  • sulfonamide 磺酰胺
  • ligand 配合体
  • spectroscopic 光谱的
  • compound 复合物
  • amino 氨基
  • benzene