Synthesis and Spectral Analysis of Pyridine Derivates
作者: Aleksandra Wojciechowska Karolina Wieszczycka Grzegorz Framski
刊名: Modern Organic Chemistry Research, 2017, Vol.2 (2)
来源数据库: Isaac Scientific Publishing
关键词: Quaternary pyridinium saltssynthesisquarterisation reactionO-alkylationprediction of activity
原始语种摘要: The present study described a detailed investigation of the synthesis of novel quaternary pyridinium salts: derivates of 1-(3-pyridine)undecane-1-one (1-propyl-3-undecanoylpyridinium bromide and 1-propyl-3-undecanoylpyridinium chloride) and N-decyloxypyridine-3-carboximidamide (3-[1-(N-decyloxyimine)ethyl]-1-propylpyridinium chloride and 3-[1-(N-decyloxyimine)ethyl]-1-propylpyridinium bromide). The structures of the products were confirmed by spectral(1H-NMR, 13C-NMR, FT-IR) analysis, mass spectrometry methods. Estimation of the pharmacotherapeutic potential has been accomplished for synthesized compounds on the basis of Prediction of Activity Spectra for Substances (PASS programe).
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  • pyridinium 吡啶盐
  • chloride 氯化物
  • pyridine 吡啶
  • propyl 丙基
  • accomplished 完成
  • ethyl 乙基
  • undecane 十一烷
  • NMR N-Modular Redundancy
  • salts 盐类
  • bromide 溴化物