LONGITUDINAL CORRELATION OF ELLIPSOID ZONE LOSS AND FUNCTIONAL LOSS IN MACULAR TELANGIECTASIA TYPE 2
作者: Tjebo F. C. HeerenDiána KitkaDaniela FloreaTraci E. ClemonsEmily Y. ChewAlan C. BirdDaniel PauleikhoffPeter Charbel IssaFrank G. HolzTunde Peto
作者单位: 1*NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom; †Department of Ophthalmology, University of Bonn, Bonn, Germany; ‡The Emmes Corporation, Rockville, Maryland; §National Eye Institute, Bethesda, Maryland; ¶Department of Ophthalmology, St Franziskus Hospital, Munster, Germany; **Oxford Eye Hospital, OUH NHS Foundation Trust and the Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford; and ††Centre for Public Health, Queenʼs University Belfast, Belfast, United Kingdom.
刊名: Retina, 2017
来源数据库: Wolters Kluwer Journal
DOI: 10.1097/IAE.0000000000001715
原始语种摘要: PURPOSE:: To compare ellipsoid zone (EZ) loss and functional loss in macular telangiectasia (MacTel) type 2 longitudinally. METHODS:: Prospective natural history study. Ellipsoid zone loss was measured in en-face images created from spectral domain optical coherence tomography. Functional loss was assessed by best-corrected visual acuity and microperimetry, counting the number of test points with impaired function. RESULTS:: A total of 56 eyes of 31 participants were followed for 4.5 ± 1.2 years. Ellipsoid zone loss was 18,600 ± 3,917.3 pixel at baseline (≈0.59 mm) and increased 2,627.8 ± 427.9 pixel (≈0.08 mm) per year. Best-corrected visual acuity decreased 2.2 ± 0.9 letters per year. Change in EZ loss correlated significantly with change in relative and absolute scotomas (r = 0.62;...
全文获取路径: Wolters Kluwer 
分享到:
来源刊物:
影响因子:2.825 (2012)

×
关键词翻译
关键词翻译
  • visual 可见
  • pixel 像素
  • points 
  • longitudinally 纵向地
  • corrected 校正的
  • coherence 相干性
  • acuity 敏锐
  • progressive 进步的
  • ellipsoid 椭圆体
  • tomography 断层x 线摄影