CORRELATION OF CLINICAL AND STRUCTURAL PROGRESSION WITH VISUAL ACUITY LOSS IN MACULAR TELANGIECTASIA TYPE 2: MacTel Project Report No. 6–The MacTel Research Group
作者: Tunde PetoTjebo F. C. HeerenTraci E. ClemonsFerenc B. SalloIrene LeungEmily Y. ChewAlan C. Bird
作者单位: 1*Centre for Public Health, Queenʼs University Belfast, Belfast, United Kingdom; †NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom; ‡University Eye Hospital, Bonn, Germany; §The Emmes Corporation, Rockville, Maryland; and ¶National Eye Institute, Bethesda, Maryland.
刊名: Retina, 2017
来源数据库: Wolters Kluwer Journal
DOI: 10.1097/IAE.0000000000001697
原始语种摘要: PURPOSE:: To evaluate progression of macular telangiectasia Type 2 lesions and their correlation with visual acuity. METHODS:: An international multicenter prospective study with annual examinations including best-corrected visual acuity (BCVA), fundus photography, fluorescein angiography, and optical coherence tomography images graded centrally. Mixed models were used to estimate progression rates, and a generalized linear model to compute the relative risk of BCVA loss, loss of ellipsoid zone (EZ) reflectivity, development of pigment plaques, or neovascularization. RESULTS:: One thousand and fourteen eyes of 507 participants were followed for 4.2 ± 1.6 years. Best-corrected visual acuity decreased 1.07 ± 0.05 letters (mean ± SE) per year. Of all eyes, 15% lost ≥15 letters after 5 years....
全文获取路径: Wolters Kluwer 
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影响因子:2.825 (2012)

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关键词翻译
关键词翻译
  • noncentral 偏心的
  • visual 可见
  • generalized 广义
  • centrally 在中心
  • fluorescein 荧光素
  • letters 信笺
  • coherence 相干性
  • acuity 敏锐
  • ellipsoid 椭圆体
  • tomography 断层x 线摄影