Hypolipidemic Effect and Antioxidant Activity of Tamarind Leaves Extract in Hypercholesterol-Fed Rats
作者: Citra Ayu ApriliaGhina NinditasariDjoko Walujo BR
作者单位: 1Pharmacology Department, Faculty of Medicine Universitas Pembangunan Nasional “Veteran”, Jakarta, Indonesia. author@ijconline.id
刊名: Indonesian Journal of Cardiology, 2017, Vol.38 (2), pp.72-80
来源数据库: The Indonesian Heart Association
DOI: 10.30701/ijc.v38i2.730
原始语种摘要: Background: Higher cost and side effects made of some anticholesterol drugs usedin long time are the reasons why some people change to herbal therapies. Tamarind(Tamarindus indica) leaves is one of the herbal therapies. This research aims to determinehypolipidemic effect and antioxidant activity of extract of tamarind leaves (ETL).Methods: We used 25 rats as samples, divided into five groups of negative control(CMC 0.5%), positive control (Ezetimibe 1.26 g/kgBW)), first, second and third doseof ETL consequently are 0.93, 1.86 and 3.73 g/kgBW.Results: Paired-samples T-test showed ETL significantly decreased total cholesterol(TC), triglyceride (TG) level, and high-density lipoprotein cholesterol (HDL-C) levelsignificantly increased compared with negative control groups (p≤0.05)....
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  • epicatechin 表儿茶酸
  • tamarind 罗望子
  • cholesterol 胆甾醇
  • antioxidant 抗氧化剂
  • hypolipidemic 降血脂药
  • flavonoid 黄酮类
  • significant 有效的
  • lipoprotein 脂蛋白
  • difference 区别
  • level 水准