Exploring cell apoptosis and senescence to understand and treat cancer: an interview with Scott Lowe
作者: Unknown
刊名: Disease Models & Mechanisms, 2015, Vol.8 (11), pp.1345-1348
来源数据库: Royal Society
DOI: 10.1242/dmm.023531
原始语种摘要: ABSTRACT Scott W. Lowe is currently principal investigator at the Memorial Sloan-Kettering Cancer Center. After beginning his studies in chemical engineering, he decided to take another path and became fascinated by biochemistry, genetics and molecular biology, which ultimately led to an interest in human disease, particularly cancer. During his PhD at the Massachusetts Institute of Technology (MIT), Scott had the opportunity to benefit from the exceptional mentorship of Earl Ruley, David Housman and Tyler Jacks, and contributed to elucidating how the p53 ( TP53 ) tumor suppressor gene limits oncogenic transformation and modulates the cytotoxic response to conventional chemotherapy. This important work earned him a fellowship from the Cold Spring Harbor Laboratory, which helped to launch...
全文获取路径: The Royal Society 
影响因子:4.959 (2012)

  • interview 采访
  • incredible 难于置信的
  • understand 理解
  • treat 处理
  • scientist 科学家
  • ultimately 最终
  • journey 旅行
  • senescence 衰老
  • cancer 癌症
  • chemotherapy 化学疗法