Multimodal Bacteriochlorophyll Theranostic Agent
作者: Tracy W.B. LiuJuan ChenLaura BurgessWeiguo CaoJiyun ShiBrian C. WilsonGang Zheng
刊名: Theranostics, 2011, Vol.1 , pp.354-362
来源数据库: Ivyspring Journal
原始语种摘要: The complimentary ability of different noninvasive imaging technologies with therapeutic modalities can be used in tandem providing high-resolution and highly sensitive imaging of events at the molecular and cellular level providing a means for image-guided therapy. There is increasing interest in using porphyrin-based photosensitizers as theranostics to take advantages of their near-infrared fluorescent properties for imaging and their strong singlet oxygen generation abilities for photodynamic therapy. Here we report a targeted multimodal bacteriochlorophyll theranostic probe. This probe consists of a bacteriochlorophyll derivative, a pharmacokinetics modification peptide linker and folate for targeted delivery to folate receptor expressing cancer cells. We demonstrate its multimodal...
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关键词翻译
关键词翻译
  • targeted 对准目标的
  • targeting 导向目标
  • imaging 图像形成
  • photodynamic 在光中发荧光的
  • therapeutic 治疗的
  • providing 只要
  • multimodal 多峰
  • capability 能力
  • receptor 接受体
  • folate 叶酸盐