The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population
作者: Jiunn-diann LinChun-Hsien HsuYao-Jen LiangWei-Cheng LianChang-Hsun HsiehChung-Ze WuDee PeiYen-Lin ChenTien-Jyun Chang
作者单位: 1Division of Endocrinology, Department of Internal Medicine, Shuang Ho Hospital, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
2Department of Family Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, New Taipei City 242, Taiwan
3Department of Life-Science, Fu-Jen University, New Taipei City 242, Taiwan
4Division of Endocrinology and Metabolism, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, School of Medicine, Hualien 970, Taiwan
5Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, Taipei 114, Taiwan
6Division of Endocrinology and Metabolism, Department of Internal Medicine, Cardinal Tien Hospital, Medical School, Fu-Jen Catholic University, New Taipei City 242, Taiwan
7Department of Pathology, Cardinal Tien Hospital, Medical School, Fu-Jen Catholic University, New Taipei City 242, Taiwan
刊名: International Journal of Endocrinology, 2015, Vol.2015
来源数据库: Hindawi Journal
DOI: 10.1155/2015/675245
原始语种摘要: Aims . There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods . Totally, 186 participants were enrolled. 75% of participants were randomly selected as the study group to build equations. The remaining 25% of participants were selected as the external validation group. All participants received a frequently sampled intravenous glucose tolerance test, and acute insulin response after the glucose load (AIRg) was obtained. The AIRg was considered as FPIS. Results . When MetS components were only used, the following equation was built: log (FPIS) = 1.477 − 0.119 × fasting plasma glucose (FPG) + 0.079 × body mass index (BMI) − 0.523...
全文获取路径: Hindawi 
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影响因子:2.518 (2012)

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关键词翻译
关键词翻译
  • insulin 胰岛素
  • fasting 禁食
  • glucose 葡萄糖
  • lipoprotein 脂蛋白
  • frequently 经常
  • cholesterol 胆甾醇
  • density 密度
  • components 零部件
  • built 建造
  • secretion 分泌