Diagnostic and Prognostic Biomarkers for Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
作者: Nilesh Kalariya Christi Bowe Joyce E. Dains
刊名: Oncology Nursing Forum, 2020, Vol.47 (2)
来源数据库: Oncology Nursing Society
DOI: 10.1188/20.ONF.E35-E43
关键词: Allogeneic hematopoietic stem cell transplantBiomarkersGraft-versus-host disease
原始语种摘要: Problem Identification: A lack of testing options for the diagnosis and prognosis of chronic graft-versus-host disease (cGVHD) is a barrier to clinical management. Studies that have investigated the role of blood proteins as diagnostic and prognostic biomarkers for cGVHD were reviewed. Literature Search: PubMed and Scopus databases were searched for articles published from January 1, 2000, to May 31, 2019. 660 articles were retrieved. Data Evaluation: The authors appraised seven articles based on the inclusion and exclusion criteria to summarize identified blood protein biomarkers for cGVHD. Synthesis: Several blood proteins were identified as potential diagnostic and prognostic biomarkers. Most of these proteins are thought to be key contributors in cGVHD pathogenesis and, therefore,...
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影响因子:2.393 (2012)

  • articles 用品
  • summarize 概括
  • published 公布的
  • hematopoietic 补血药
  • preemptive 抢先
  • proteins 蛋白质
  • barrier 堡坝
  • blood 血液
  • exclusion 排除
  • management 管理