Radio-sensitization of SHG44 glioma cells by Aidi injection in vitro
作者: Xiao-Ting XuYao SongSongbing QinLi-Li WangJu-Ying Zhou
作者单位: 1Department of Radiation Oncology, The First Affiliated HospitalOf Soochow University, Suzhou, Jiangsu 215006, P.R. China
刊名: Molecular Medicine Reports, 2012, Vol.5 (6), pp.1415-1418
来源数据库: Spandidos Journal
DOI: 10.3892/mmr.2012.836
原始语种摘要: In this study, we aimed to explore the radio-sensitization of the SHG44glioma cell line by Aidi injection and the possible mechanisms involved. The growthcurve, cloning efficiency and divisional index of the SHG44 cell line were observed.The inhibition ratio was determined by MTT assay, the change in the cell cyclewas analyzed by flow cytometry and the expression of cyclin B1 and Wee1 was detectedby western blot analysis. The reproductive activity of the group treated withirradiation (IR) and Aidi injection was suppressed significantly, and the cloningefficiency and divisional index also declined. Aidi injection (15 µg/ml) inducedG2/M phase arrest efficiently in the cell line after 48 h. The expression of cyclin B1decreased in the group treated with IR and Aidi injection compared with...
全文获取路径: Spandidos 
分享到:

×
关键词翻译
关键词翻译
  • injection 贯入
  • sensitization 激活
  • SHG 二次谐波产生
  • glioma 神经胶质瘤
  • divisional 分部的
  • cyclin 细胞周期蛋白
  • expression 表示
  • declined 先端下倾的
  • arrest 制动器
  • phase 相位