Aortic calcification, arterial stiffness and bone mineral density in patients with COPD☆
作者: Charlotte E. BoltonCarmel M. McEnieryVimal RajBarry J. McDonnellAdrian K. DixonMargaret MunneryRamsey SabitNicholas ScreatonMichael StoneIan B. WilkinsonDennis J. ShaleJohn R. Cockcroft
刊名: Artery Research, 2011, Vol.5 (1)
来源数据库: Atlantis Press
DOI: 10.1016/j.artres.2011.01.001
原始语种摘要: Background: Increased arterial stiffness, using aortic pulse wave velocity (PWV) has been demonstrated in patients with COPD. However, mechanisms underlying this remain unclear. We explored the contribution of aortic calcification to large artery haemodynamics and its association to bone mineral density (BMD) in patients with confirmed COPD.Methods: Patients with COPD, free of maintenance oral corticosteroids, renal disease, diabetes or known cardiovascular disease (n = 45), 27 male, mean (SD) age 66(7) years underwent unenhanced thoraco-abdominal computed tomography to determine quantitative aortic calcium content using a volume scoring method. Aortic PWV was measured. A subgroup (n = 29) had BMD determined.Results: All patients had some evidence of aortic calcification. Aortic PWV was...
全文获取路径: Atlantis出版社 

  • calcification 钙化
  • arterial 动脉的
  • stiffness 刚性
  • aortic 织脉的
  • density 密度
  • abdominal 腹部的
  • mineral 矿物
  • descending 
  • aorta 织脉
  • ascending 上升的