The chondrogenic differentiation potential of dental pulp stem cells
作者: A LongoniI E van HooijdonkG K BittermannV C VetterE C Kruijt SpanjerJ RossA J RosenbergD Gawlitta
作者单位: 1University Medical Centre Utrecht, Department of Oral and Maxillofacial Surgery and Special Dental Care, room G05.129, PO Box 85500, 3508 GA Utrecht, the Netherlands. d.gawlitta@umcutrecht.nl
刊名: Eur Cell Mater, 2020, Vol.39 , pp.121-135
来源数据库: European Cells and Materials (eCM)
DOI: 10.22203/eCM.v039a08
原始语种摘要: Dental pulp stem cells (DPSCs) are particularly promising for tissue engineering (TE) due to the ease of their isolation procedure, great expansion potential and capability to differentiate towards several cell types of the mesodermal, ectodermal and endodermal lineages. Although several studies hint that DPSCs exhibit potential for cartilage tissue formation, the chondrogenic potential of DPSCs has only been marginally explored. Thus, the aim of the present study was to closely investigate the chondrogenic differentiation capacity of DPSCs for TE applications. More specifically, the potential of DPSCs for engineering hyaline and fibrous cartilage was determined.DPSCs obtained from 7 human molars were expanded and chondrogenically differentiated in a 3D pellet culture model. After 21 d of...
全文获取路径: European Cells and Materials (eCM) 
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影响因子:4.558 (2012)

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关键词翻译
关键词翻译
  • potential 
  • cartilage 软骨
  • mesodermal 中表层的
  • endodermal 内胚层的
  • cells 麻风细胞
  • ectodermal 外胚层的
  • collagen 胶骨硬蛋白质
  • differentiate 微分
  • hyaline 玻璃质的
  • inductive 电感的