VIRULENCE FACTORS CORRELATION AMONG AmpC AND ESBL PRODUCING Klebsiella pneumoniae CLINICAL ISOLATES
产肺炎克雷伯菌临床分离株AmpC和ESBL的毒力因子相关性
作者: B. ADITI PRIYADARSHINIKRISHNAN MAHALAKSHMI
作者单位: 1Department of Microbiology, Bharath Institute of Higher Education and Research, Selaiyur, Chennai-73, India.
2Department of Microbiology, Sree Balaji Dental College and Hospital, Chennai- 100 India.
刊名: PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 2020, pp.59-64
来源数据库: International Knowledge Press
关键词: AmpCExtended spectrum beta lactamasesMrkDUgeVirulence.
原始语种摘要: Introduction: Multi drug resistant Klebsiella pneumoniae is a major threat to public health. AmpC beta lactamases and extended spectrum beta lactamases (ESBL) producing Klebsiella pneumoniae isolates hydrolyze the commonly used cephalosporin group of antibiotics rendering them ineffective in curbing the infections. Capsule lipopolysaccharides, fimbriae, siderophores and adhesions are major virulence factors in pathogenicity of K. pneumoniae. Our study aimed at evaluating the relationship between virulence and antibiotic resistance in the K. pneumoniae clinical isolates. Materials and Methods: A total of 234 K. pneumoniae isolates were collected from a tertiary care hospital. Antibiotic susceptibility testing was performed by Vitek 2 systems version 7.0. Phenotypic screening for AmpCs and...
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关键词翻译
关键词翻译
  • isolates 单离体
  • antibiotic 抗生素
  • virulence 病毒性
  • ceftriaxone 头孢三嗪
  • cefotetan 头孢替坦
  • lactamase 内酰胺酶
  • susceptibility 磁化率
  • cephalosporin 头孢菌素
  • resistant 耐久的
  • major 知的